Proviron

Proviron (mesterolone) is an interesting anabolic steroid, though it is not of much value to bodybuilding..

It seems that the most common reason for many to consider including it in a steroid stack is for anti-estrogenic activity. In the days before anti-aromatases and the use of SERMs (selective estrogen receptor modulators) such as Clomid and Nolvadex, there was some merit to this. An amount of aromatizing steroid marginally over the amount that would be tolerable without Proviron became tolerable with the inclusion of it.

However, the effect is indeed only marginal, and much better anti-estrogenic agents now exist. When these are used, there is no need for Proviron as an anti-estrogen.

The mechanism by which it has some effectiveness in this regard is from binding weakly to the estrogen receptor without activating it, and to the aromatase enzyme. In the first case, this partially reduces the number of receptor sites momentarily available to bind estrogen, thus reducing estrogenic activity. In the second case, some fraction of aromatase molecules at any given moment are unavailable to bind and convert testosterone, their binding sites being occupied with mesterolone.

The second most common reason is probably to address a fear that libido might be lost without it. It is true that when added to normal androgen levels, Proviron has an androgenic effect that in many cases improves libido. However, most anabolic steroids also have this same property. In a steroid cycle, adding Proviron accomplishes nothing further. Or in the case of anabolic steroids such as nandrolone (Deca) which for other reasons may adversely affect libido, Proviron provides no greater help against that than do various other anabolic steroids.

30 GBP Provironum 25mg 50 tablets